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| Name | Developing novel treatment approaches for hereditary hemorrhagic telangiectasia |
| Video Uploader | Video From VJHemOnc – Video Journal of Hematology & HemOnc |
| Upload Date | This Video Uploaded At 01-06-2023 10:13:32 |
| Video Discription | Hanny Al-Samkari, MD, Massachusetts General Hospital, Boston, MA, discusses the current lack of approved treatments for patients with hereditary hemorrhagic telangiectasia (HHT). Dr Al-Samkari provides an overview of the pathophysiology and primary symptoms of HHT and further describes two categories of therapeutics under development: drugs repurposed from cancer treatment, such as bevacizumab, thalidomide, and pomalidomide, and drugs being specifically developed for HHT, such as the allosteric AKT inhibitor VAD044. Of these agents, Dr Al-Samkari notes that bevacizumab, pomalidomide, and VAD044 are the subjects of ongoing clinical trials. This interview took place at the 63rd Annual Scientific Meeting of the British Society for Haematology (BSH) 2023, held in Birmingham, UK. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved. |
| Category | Education |
| Tags | Speaker: Hanny Al-Samkari | Institution: Massachusetts General Hospital | Event: BSH 2023 | Format: Interview | Subject: Hereditary Hemorrhagic Telangiectasia | Subject: Rare diseases | Field: Treatment | Field: Perspectives | Field: Disease Biology | Field: Trial Updates | Field: Policy | Field: Immuno-oncology | Medicines: Bevacizumab | Medicines: Thalidomide | Medicines: Pomalidomide | Medicines: VAD044 | Medicines: Antibodies | HHT | NCT05406362 |
