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| Name | Gut Microbiota and Mood: Can you eat your way to happiness? |
| Video Uploader | Video From Demystifying Medicine McMaster |
| Upload Date | This Video Uploaded At 10-03-2022 21:00:12 |
| Video Discription | This video discusses recent discoveries that reveal a link between gut microbial composition and mood disorders. It outlines the role of serotonin in the body and discusses a set of studies that test the role of gut bacteria in regulating human mood. This video also discusses the limitations in the scientific literature, future directions, and the potential use of bacteria in mood disorder treatment. This video was made by McMaster students Hani Fakhri, Sabhat Khan, and Pukhraj Gaheer in collaboration with the McMaster Demystifying Medicine Program. Subscribe to the McMaster Demystifying Medicine YouTube channel: https://www.youtube.com/c/DemystifyingMedicine This video is provided for general and educational information only. Please consult your health care provider for information about your health Copyright McMaster University 2022 #DemystifyingMedicine #MentalHealth References: Aizawa E, Tsuji H, Asahara T, Takahashi T, Teraishi T, Yoshida S, et al. Possible association of bifidobacterium and lactobacillus in the gut microbiota of patients with major depressive disorder. Journal of Affective Disorders. 2016;202:254–7. Akkasheh, G., Kashani-Poor, Z., Tajabadi-Ebrahimi, M., Jafari, P., Akbari, H., Taghizadeh, M., Memarzadeh, M. R., Asemi, Z., & Esmaillzadeh, A. (2016). Clinical and metabolic response to probiotic administration in patients with major depressive disorder: A randomized, double-blind, placebo-controlled trial. Nutrition, 32(3), 315–320. https://doi.org/10.1016/j.nut.2015.09.003 Breit, S., Kupferberg, A., Rogler, G., & Hasler, G. (2018). Vagus nerve as modulator of the brain–gut axis in psychiatric and inflammatory disorders. Frontiers in Psychiatry, 9. https://doi.org/10.3389/fpsyt.2018.00044 Cheng L-H, Liu Y-W, Wu C-C, Wang S, Tsai Y-C. Psychobiotics in mental health, neurodegenerative and neurodevelopmental disorders. Journal of Food and Drug Analysis. 2019;27(3):632–48. Fung TC, Vuong HE, Luna CD, ****ovost GN, Aleksandrova AA, Riley NG, et al. Intestinal serotonin and fluoxetine exposure modulate bacterial colonization in the gut. Nature Microbiology. 2019;4(12):2064–73. Huang T-T, Lai J-B, Du Y-L, Xu Y, Ruan L-M, Hu S-H. Current understanding of gut microbiota in mood disorders: An update of human studies. Frontiers in Genetics. 2019;10. Li N, Wang Q, Wang Y, Sun A, Lin Y, Jin Y, et al. Fecal microbiota transplantation from chronic unpredictable mild stress mice donors affects anxiety-like and depression-like behavior in recipient mice via the gut microbiota-inflammation-brain axis. Stress. 2019;22(5):592–602. MOHAMMAD-ZADEH, L. F., MOSES, L., & GWALTNEY-BRANT, S. M. (2008). Serotonin: A Review. Journal of Veterinary Pharmacology and Therapeutics, 31(3), 187–199. https://doi.org/10.1111/j.1365-2885.2008.00944.x Scaccia A. Serotonin: Functions, normal range, side effects, and more [Internet]. Healthline. Healthline Media; 2020 [cited 2022Jan22]. Available from: https://www.healthline.com/health/mental-health/serotonin Singhal, M., Turturice, B. A., Manzella, C. R., Ranjan, R., Metwally, A. A., Theorell, J., Huang, Y., Alrefai, W. A., Dudeja, P. K., Finn, P. W., Perkins, D. L., & Gill, R. K. (2019). Serotonin transporter deficiency is associated with dysbiosis and changes in metabolic function of the mouse intestinal microbiome. Scientific Reports, 9(1). https://doi.org/10.1038/s41598-019-38489-8 Slykerman RF, Hood F, Wickens K, Thompson JMD, Barthow C, Murphy R, et al. Effect of lactobacillus rhamnosus HN001 in pregnancy on postpartum symptoms of depression and anxiety: A randomised double-blind placebo-controlled trial. EBioMedicine. 2017;24:159–65. Steenbergen, L., Sellaro, R., van Hemert, S., Bosch, J. A., & Colzato, L. S. (2015). A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood. Brain, Behavior, and Immunity, 48, 258–264. https://doi.org/10.1016/j.bbi.2015.04.003 Terry, N., & Margolis, K. G. (2016). Serotonergic mechanisms regulating the GI tract: Experimental evidence and therapeutic relevance. Gastrointestinal Pharmacology, 319–342. https://doi.org/10.1007/164_2016_103 Wallace, C. J., & Milev, R. (2017). The effects of probiotics on depressive symptoms in humans: A systematic review. Annals of General Psychiatry, 16(1). https://doi.org/10.1186/s12991-017-0138-2 |
| Category | Education |
| Tags | McMaster University | Demystifying Medicine |
